Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
truncated, soluble form | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha-meso-hydroxyhemin IX + reduced acceptor + O2 | - |
Rattus norvegicus | verdoheme IXalpha + CO + acceptor + H2O | - |
? | |
beta-meso-hydroxyhemin IX + reduced acceptor + O2 | - |
Rattus norvegicus | verdoheme IXbeta + CO + acceptor + H2O | - |
? | |
delta-meso-hydroxyhemin IX + reduced acceptor + O2 | - |
Rattus norvegicus | verdoheme IXdelta + CO + acceptor + H2O | - |
? | |
gamma-meso-hydroxyhemin IX + reduced acceptor + O2 | - |
Rattus norvegicus | verdoheme IXgamma + CO + acceptor + H2O | - |
? | |
hemin + reduced acceptor + O2 | - |
Rattus norvegicus | alpha-meso-hydroxyhemin IX + CO + acceptor + H2O | - |
? | |
additional information | reaction proceeds via three steps, first step is alpha-regioselective hydroxylation of hemin, second degradation of meso-hydroxyhemin to verdoheme and third degradation of verdoheme to biliverdin, which again is stereoselective for verdoheme IXalpha. In the second step, enzyme would convert all four isomers of meso-hydroxyhemin | Rattus norvegicus | ? | - |
? | |
verdoheme IXalpha + H2O | - |
Rattus norvegicus | biliverdin IXalpha + Fe2+ | - |
? |