Literature summary for 1.14.14.15 extracted from

Van Lanen, S.G.; Dorrestein, P.C.; Christenson, S.D.; Liu, W.; Ju, J.; Kelleher, N.L.; Shen, B.
Biosynthesis of the beta-amino acid moiety of the enediyne antitumor antibiotic C-1027 featuring beta-amino acyl-S-carrier protein intermediates (2005), J. Am. Chem. Soc., 127, 11594-11595.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] + FADH2 + O2	Streptomyces globisporus	-	(3S)-3-amino-3-(3-chloro-4,5-dihydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] + FAD + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Streptomyces globisporus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] + FADH2 + O2	-	Streptomyces globisporus	(3S)-3-amino-3-(3-chloro-4,5-dihydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] + FAD + H2O	-	?
beta-aminoacyl-S-SgcC + FADH2 + O2	-	Streptomyces globisporus	?	-	?

Synonyms

Synonyms	Comment	Organism
SgcC3	-	Streptomyces globisporus

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Release 2023.1 (January 2023)