Cloned (Comment) | Organism |
---|---|
- |
Neogale vison |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Neogale vison | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
57900 | - |
sequence analysis | Neogale vison |
58500 | - |
sequence analysis | Neogale vison |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Neogale vison | A7UDB5 | - |
- |
Neogale vison | A7UDB6 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Neogale vison | - |
lung | - |
Neogale vison | - |
Synonyms | Comment | Organism |
---|---|---|
CYP1A1 | - |
Neogale vison |
CYP1A2 | - |
Neogale vison |
Organism | Comment | Expression |
---|---|---|
Neogale vison | exposure to both 2,3,7,8-tetrachlorodibenzofuran and 2,3,4,7,8-pentachlorodibenzofuran results in dose-dependent increase of CYP1A2 mRNA due to an underlying aryl hydrocarbon receptor-mediated mechanism | up |
Neogale vison | exposure to both 2,3,7,8-tetrachlorodibenzofuran and 2,3,4,7,8-pentachlorodibenzofuran results in dose-dependent increases of CYP1A1 mRNA and CYP1A protein levels due to an underlying aryl hydrocarbon receptor-mediated mechanism. Upregulation of CYP1A mRNA in liver is more consistent to the sum adipose 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalent concentration than to the liver 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalent concentration in minks treated with 2,3,7,8-tetrachlorodibenzofuran or 2,3,4,7,8-pentachlorodibenzofuran | up |