Cloned (Comment) | Organism |
---|---|
- |
Pseudomonas fluorescens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benzoylalanine | KMO inhibitor that mimics the substrate structure, and also stimulates reduction of the flavin by NADPH | Pseudomonas fluorescens | |
m-nitrobenzoylalanine | KMO inhibitor that mimics the substrate structure, and also stimulates reduction of the flavin by NADPH | Pseudomonas fluorescens | |
additional information | targeted inhibition of KMO is a viable strategy for achieving local elevation of kynurenate concentrations | Pseudomonas fluorescens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
NaCl | stabilizes | Pseudomonas fluorescens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas fluorescens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Pseudomonas fluorescens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-kynurenine + NADPH + O2 | binding of L-kynurenine to the oxidized enzyme is relatively slow and involves at least two reversible steps | Pseudomonas fluorescens | 3-hydroxy-L-kynurenine + NADP+ + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
KMO | - |
Pseudomonas fluorescens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Pseudomonas fluorescens | |
NADPH | - |
Pseudomonas fluorescens |