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Literature summary for 1.14.13.8 extracted from

  • Lee, J.K.; Kang, J.H.; Cha, Y.N.; Chung, W.G.; Park, C.S.
    Alteration of substrate specificity by common variants, E158K/E308G and V257M, in human hepatic drug-metabolizing enzyme, flavin-containing monooxygenase 3 (2003), Korean J. Physiol. Pharmacol., 7, 157-162.
No PubMed abstract available

Protein Variants

Protein Variants Comment Organism
V257M variant with 13.21% allele frequency. Mutation causes a transformation of the secondary structure. The presence of this mutant allele correlates significantly with a reduction in caffeine N-1-demethylating activity Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
flavin-containing monooxygenase 3
-
Homo sapiens