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Literature summary for 1.14.13.8 extracted from
- The role of porcine thyroid peroxidase and FAD-containing monooxygenase in the metabolism of 1-methyl-2-thioimidazole (methimazole) (1983), Biochem. Biophys. Res. Commun., 116, 449-455.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| n-octylamine | thyroid enzyme only active in presence of n-octylamine | Sus scrofa |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| thyroid gland | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-methyl-2-thioimidazole + NADPH + O2 | - |
Sus scrofa | ? | - |
? | |
| methimazole + NADPH + O2 | - |
Sus scrofa | N-methylmethimidazole-2-sulfinic acid + NADP+ + H2O | - |
? | |
| N,N-dimethylaniline + NADPH + O2 | - |
Sus scrofa | N,N-dimethylaniline N-oxide + NADP+ + H2O | - |
? | |
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