Literature summary for 1.14.13.39 extracted from

Novaretti, N.; Padovan-Neto, F.E.; Tumas, V.; da-Silva, C.A.; Del Bel, E.A.
Lack of tolerance for the anti-dyskinetic effects of 7-nitroindazole, a neuronal nitric oxide synthase inhibitor, in rats (2010), Braz. J. Med. Biol. Res., 43, 1047-1053.

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Inhibitors

Inhibitors	Comment	Organism	Structure
7-nitroindazole	inhibits the neuronal NOS in vivo and reduces L-DOPA-induced dyskinesias in a rat model of parkinsonism. The rats show a lack of tolerance for the anti-dyskinetic effects	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	male	-
Rattus norvegicus Wistar	-	male	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	from rats with unilateral depletion of dopamine in the substantia nigra compacta treated with L-DOPA at 30 mg/kg body weight for 34 days, nNOS expression is restricted to neurons	Rattus norvegicus	-
neuron	-	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
neuronal nitric oxide synthase	-	Rattus norvegicus
nNOS	-	Rattus norvegicus
NO synthase	-	Rattus norvegicus

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Release 2023.1 (January 2023)