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Literature summary for 1.14.13.234 extracted from

  • Binnie, C.; Warren, M.; Butler, M.
    Cloning and heterologous expression in Streptomyces lividans of Streptomyces rimosus genes involved in oxytetracycline biosynthesis (1989), J. Bacteriol., 171, 887-895.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Streptomyces rimosus Q55001 bifunctional enzyme, catalyzes the stereospecific hydroxylation of anhydrotetracycline at C-6 (EC 1.14.13.38) and performs an additional hydroxylation at C-5, producing 5a,11a-dehydrooxytetracycline, reaction of EC 1.14.13.234
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Synonyms

Synonyms Comment Organism
anhydrotetracycline oxygenase
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Streptomyces rimosus
OtcC
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Streptomyces rimosus

Cofactor

Cofactor Comment Organism Structure
NADPH
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Streptomyces rimosus

General Information

General Information Comment Organism
physiological function heterologous expression in Streptomyces lividans grown on solid or in liquid medium enables the production of oxytetracycline Streptomyces rimosus