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Literature summary for 1.14.13.2 extracted from
- On the interaction of para-hydroxybenzoate hydroxylase from Pseudomonas fluorescens with halogen ions (1973), FEBS Lett., 36, 177-180.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Br- | competitive with respect to NADPH | Pseudomonas fluorescens |  |
| Cl- | competitive with respect to NADPH | Pseudomonas fluorescens | |
| CNS- | competitive with respect to NADPH | Pseudomonas fluorescens | |
| F- | competitive with respect to NADPH | Pseudomonas fluorescens | |
| I- | competitive with respect to NADPH | Pseudomonas fluorescens | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-hydroxybenzoate + NADPH + O2 | Pseudomonas fluorescens | inducible enzyme | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas fluorescens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-hydroxybenzoate + NADPH + O2 | - |
Pseudomonas fluorescens | protocatechuate + NADP+ + H2O | - |
? | |
| 4-hydroxybenzoate + NADPH + O2 | inducible enzyme | Pseudomonas fluorescens | ? | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Pseudomonas fluorescens | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 5.9 | - |
Cl- | - |
Pseudomonas fluorescens | |
| 6 | - |
CNS- | - |
Pseudomonas fluorescens | |
| 9.7 | - |
I- | - |
Pseudomonas fluorescens | |
| 65 | - |
Br- | - |
Pseudomonas fluorescens | |
| 150 | - |
F- | - |
Pseudomonas fluorescens | |
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