Organism | UniProt | Comment | Textmining |
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Pseudomonas putida | - |
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Pseudomonas putida UV4 | - |
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Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
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3-(propan-2-yl)benzene-1,2-diol + NADH + H+ + O2 | - |
Pseudomonas putida | (4R,5S)-4,5-dihydroxy-3-(propan-2-yl)cyclohex-2-en-1-one + NAD+ | alkyl-substituted cyclohexenone cis-diols are formed as the most significant metabolites prior to extraction. In addition to the cyclohexenone cis-diols, (4R,5S)-4,5-dihydroxy-3-(propan-2-yl)cyclohex-2-en-1-one, and triols, (1R,2S,4R)-6-(propan-2-yl)cyclohex-5-ene-1,2,4-triol, are obtained from biotransformation of the phenol parent compound in strain UV4 cultures | ? | |
3-(propan-2-yl)benzene-1,2-diol + NADH + H+ + O2 | - |
Pseudomonas putida UV4 | (4R,5S)-4,5-dihydroxy-3-(propan-2-yl)cyclohex-2-en-1-one + NAD+ | alkyl-substituted cyclohexenone cis-diols are formed as the most significant metabolites prior to extraction. In addition to the cyclohexenone cis-diols, (4R,5S)-4,5-dihydroxy-3-(propan-2-yl)cyclohex-2-en-1-one, and triols, (1R,2S,4R)-6-(propan-2-yl)cyclohex-5-ene-1,2,4-triol, are obtained from biotransformation of the phenol parent compound in strain UV4 cultures | ? | |
3-(trifluoromethyl)benzene-1,2-diol + NADH + H+ + O2 | - |
Pseudomonas putida | (4R,5S)-4,5-dihydroxy-3-(trifluoromethyl)cyclohex-2-en-1-one + NAD+ | alkyl-substituted cyclohexenone cis-diols are formed as the most significant metabolites prior to extraction. In addition to the cyclohexenone cis-diols, (4R,5S)-4,5-dihydroxy-3-(trifluoromethyl)cyclohex-2-en-1-one, and triols, (1R,2S,4R)-6-(trifluoromethyl)cyclohex-5-ene-1,2,4-triol, are obtained from biotransformation of the phenol parent compound in strain UV4 cultures | ? | |
3-(trifluoromethyl)benzene-1,2-diol + NADH + H+ + O2 | - |
Pseudomonas putida UV4 | (4R,5S)-4,5-dihydroxy-3-(trifluoromethyl)cyclohex-2-en-1-one + NAD+ | alkyl-substituted cyclohexenone cis-diols are formed as the most significant metabolites prior to extraction. In addition to the cyclohexenone cis-diols, (4R,5S)-4,5-dihydroxy-3-(trifluoromethyl)cyclohex-2-en-1-one, and triols, (1R,2S,4R)-6-(trifluoromethyl)cyclohex-5-ene-1,2,4-triol, are obtained from biotransformation of the phenol parent compound in strain UV4 cultures | ? | |
3-ethylbenzene-1,2-diol + NADH + H+ + O2 | - |
Pseudomonas putida | (4R,5S)-3-ethyl-4,5-dihydroxycyclohex-2-en-1-one + NAD+ | alkyl-substituted cyclohexenone cis-diols are formed as the most significant metabolites prior to extraction. In addition to the cyclohexenone cis-diols, (4R,5S)-3-ethyl-4,5-dihydroxycyclohex-2-en-1-one, and triols, (1R,2S,4R)-6-ethylcyclohex-5-ene-1,2,4-triol, are obtained from biotransformation of the phenol parent compound in strain UV4 cultures | ? | |
3-ethylbenzene-1,2-diol + NADH + H+ + O2 | - |
Pseudomonas putida UV4 | (4R,5S)-3-ethyl-4,5-dihydroxycyclohex-2-en-1-one + NAD+ | alkyl-substituted cyclohexenone cis-diols are formed as the most significant metabolites prior to extraction. In addition to the cyclohexenone cis-diols, (4R,5S)-3-ethyl-4,5-dihydroxycyclohex-2-en-1-one, and triols, (1R,2S,4R)-6-ethylcyclohex-5-ene-1,2,4-triol, are obtained from biotransformation of the phenol parent compound in strain UV4 cultures | ? | |
3-iodobenzene-1,2-diol + NADH + H+ + O2 | - |
Pseudomonas putida | (4S,5S)-4,5-dihydroxy-3-iodocyclohex-2-en-1-one + NAD+ | alkyl-substituted cyclohexenone cis-diols are formed as the most significant metabolites prior to extraction | ? | |
3-iodobenzene-1,2-diol + NADH + H+ + O2 | - |
Pseudomonas putida UV4 | (4S,5S)-4,5-dihydroxy-3-iodocyclohex-2-en-1-one + NAD+ | alkyl-substituted cyclohexenone cis-diols are formed as the most significant metabolites prior to extraction | ? | |
3-methylbenzene-1,2-diol + NADH + H+ + O2 | - |
Pseudomonas putida | (4R,5S)-4,5-dihydroxy-3-methylcyclohex-2-en-1-one + NAD+ | alkyl-substituted cyclohexenone cis-diols are formed as the most significant metabolites prior to extraction | ? | |
3-tert-butylbenzene-1,2-diol + NADH + H+ + O2 | - |
Pseudomonas putida | (4R,5S)-3-tert-butyl-4,5-dihydroxycyclohex-2-en-1-one + NAD+ | alkyl-substituted cyclohexenone cis-diols are formed as the most significant metabolites prior to extraction. In addition to the cyclohexenone cis-diols, (4R,5S)-3-tert-butyl-4,5-dihydroxycyclohex-2-en-1-one, and triols, (1R,2S,4R)-6-tert-butylcyclohex-5-ene-1,2,4-triol, are obtained from biotransformation of the phenol parent compound in strain UV4 cultures | ? | |
biphenyl-2,3-diol + NADH + H+ + O2 | - |
Pseudomonas putida | (4R,5S)-4,5-dihydroxy-3-phenylcyclohex-2-en-1-one + NAD+ | alkyl-substituted cyclohexenone cis-diols are formed as the most significant metabolites prior to extraction. In addition to the cyclohexenone cis-diols, (4R,5S)-4,5-dihydroxy-3-phenylcyclohex-2-en-1-one, and triols, (1R,2S,4R)-6-phenylcyclohex-5-ene-1,2,4-triol, are obtained from biotransformation of the phenol parent compound in strain UV4 cultures | ? | |
additional information | dioxygenase-catalysed cis-dihydroxylation of meta-substituted phenols to yield cyclohexenone cis-diol and derived enantiopure cis-triol metabolites, overview. Formation of enantiopure cyclohexenone cis-diol metabolites and binding interactions of the m-phenol substrates at the active site of toluene dioxygenase, overview. Product analysis by NMR | Pseudomonas putida | ? | - |
? | |
additional information | dioxygenase-catalysed cis-dihydroxylation of meta-substituted phenols to yield cyclohexenone cis-diol and derived enantiopure cis-triol metabolites, overview. Formation of enantiopure cyclohexenone cis-diol metabolites and binding interactions of the m-phenol substrates at the active site of toluene dioxygenase, overview. Product analysis by NMR | Pseudomonas putida UV4 | ? | - |
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Synonyms | Comment | Organism |
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TDO | - |
Pseudomonas putida |
General Information | Comment | Organism |
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metabolism | the enzyme is involved in aromatic hydroxylation and mineralization pathways converting arenes into cis-dihydrodiols, overview | Pseudomonas putida |