Literature summary for 1.14.11.53 extracted from

Liu, K.; Ding, Y.; Ye, W.; Liu, Y.; Yang, J.; Liu, J.; Qi, C.
Structural and functional characterization of the proteins responsible for N6-methyladenosine modification and recognition (2016), Curr. Protein Pept. Sci., 17, 306-318.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
N6-methyladenine in mRNA + 2-oxoglutarate + O2	Homo sapiens	m6A modification preferentially appears after G in the conserved motif RRm6ACH (R is A/G and H is A/C/U)	adenine in mRNA + formaldehyde + succinate + CO2	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
N6-methyladenine in mRNA + 2-oxoglutarate + O2	m6A modification preferentially appears after G in the conserved motif RRm6ACH (R is A/G and H is A/C/U)	Homo sapiens	adenine in mRNA + formaldehyde + succinate + CO2	-	?

Synonyms

Synonyms	Comment	Organism
AlkB homolog 5	-	Homo sapiens
ALKBH5	-	Homo sapiens

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Release 2023.1 (January 2023)