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Literature summary for 1.14.11.48 extracted from

  • Cultrone, A.; Scazzocchio, C.; Rochet, M.; Montero-Moran, G.; Drevet, C.; Fernandez-Martin, R.
    Convergent evolution of hydroxylation mechanisms in the fungal kingdom: molybdenum cofactor-independent hydroxylation of xanthine via alpha-ketoglutarate-dependent dioxygenases (2005), Mol. Microbiol., 57, 276-290.
    View publication on PubMed
Search for more literature for 1.14.11.48

Cloned(Commentary)

Cloned (Comment) Organism
-
 Aspergillus nidulans

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
 Aspergillus nidulans

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 xanthine KM-value determined in crude extract: 0.023 mM Aspergillus nidulans
additional information
-
 2-oxoglutarate KM-value determined in crude extract: 0.05 mM Aspergillus nidulans

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ Fe2+-dependent enzyme Aspergillus nidulans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
xanthine + 2-oxoglutarate + O2 Aspergillus nidulans
-
 urate + succinate + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Aspergillus nidulans Q4QZZ9
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
xanthine + 2-oxoglutarate + O2
-
 Aspergillus nidulans urate + succinate + CO2
-
 ?

Synonyms

Synonyms Comment Organism
alpha-ketoglutarate-dependent xanthine hydroxylase
-
 Aspergillus nidulans
XanA
-
 Aspergillus nidulans

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Aspergillus nidulans

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.9
-
 assay at Aspergillus nidulans