Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2-amino-4-hydroxy-6,7-dimethyltetrahydropteridine | can replace ascorbate | Gallus gallus | |
2-mercaptoethanol | can replace ascorbate | Gallus gallus | |
dithiothreitol | can replace ascorbate | Gallus gallus | |
L-cysteine | can replace ascorbate | Gallus gallus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.04 | 0.05 | O2 | - |
Gallus gallus | |
0.05 | - |
2-oxoglutarate | - |
Gallus gallus | |
0.09 | 0.12 | 2-oxoglutarate | - |
Gallus gallus | |
0.19 | 0.22 | ascorbate | - |
Gallus gallus | |
0.4 | 0.5 | Procollagen L-lysine | - |
Gallus gallus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | required, Km: 0.001-0.005 mM | Gallus gallus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryo | - |
Gallus gallus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-oxoglutarate + O2 + ascorbate | uncoupled decarboxylation in absence of peptide substrate | Gallus gallus | succinate + CO2 + dehydroascorbate + H2O | - |
? | |
peptidyl-L-lysine + 2-oxoglutarate + O2 | - |
Gallus gallus | peptidyl-5-hydroxy-L-lysine + succinate + CO2 | - |
? | |
[procollagen] L-lysine + 2-oxoglutarate + O2 | - |
Gallus gallus | [procollagen]-(2S,5R)-5-hydroxy-L-lysine + succinate + CO2 | - |
r |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ascorbate | required | Gallus gallus |