Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
additional information | vindoline biosynthesis pathway enzyme subcellular localization study, overview | Catharanthus roseus | - |
- |
nucleoplasm | the enzyme resides in the nucleocytoplasmic compartment following passive diffusion to the nucleus allowed by the protein size. Colocalization with deacetylvindoline-4-O-acetyltransferase | Catharanthus roseus | 5654 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
deacetoxyvindoline + 2-oxoglutarate + O2 | Catharanthus roseus | - |
deacetylvindoline + succinate + CO2 | - |
? | |
additional information | Catharanthus roseus | the desacetoxyvindoline-4-hydroxylase interacts with the deacetylvindoline-4-O-acetyltransferase, analysis via yeast two-hybrid system | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Catharanthus roseus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
idioblast | - |
Catharanthus roseus | - |
laticifer | - |
Catharanthus roseus | - |
leaf | - |
Catharanthus roseus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
deacetoxyvindoline + 2-oxoglutarate + O2 | - |
Catharanthus roseus | deacetylvindoline + succinate + CO2 | - |
? | |
additional information | the desacetoxyvindoline-4-hydroxylase interacts with the deacetylvindoline-4-O-acetyltransferase, analysis via yeast two-hybrid system | Catharanthus roseus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | - |
Catharanthus roseus |
Synonyms | Comment | Organism |
---|---|---|
D4H | - |
Catharanthus roseus |
desacetoxyvindoline-4-hydroxylase | - |
Catharanthus roseus |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme catalyzes the penultimate step in the biosynthesis of vindoline, which constitutes the main terpenoid indole alkaloid accumulated in leaves of Catharanthus roseus, spatial organization of the vindoline biosynthetic pathway, overview. The desacetoxyvindoline-4-hydroxylase interacts directly with the deacetylvindoline-4-O-acetyltransferase, that catalyzes the last step of the biosynthetic pathway, absence of metabolic channeling in the vindoline biosynthetic pathway. Importance of inter- and intracellular translocations of intermediates during the vindoline biosynthesis and potential regulatory role, overview | Catharanthus roseus |