Literature summary for 1.14.11.2 extracted from

Callapina, M.; Zhou, J.; Schnitzer, S.; Metzen, E.; Lohr, C.; Deitmer, J.W.; Bruene, B.
Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation--implications for prolyl hydroxylase activity and iron (2005), Exp. Cell Res., 306, 274-284.

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Metals/Ions

Metals/Ions	Comment	Organism	Structure
Fe2+	0.5 mM	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HEK-293 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
hypoxia-inducible factor L-proline + 2-oxoglutarate + O2	-	Homo sapiens	hypoxia-inducible factor trans-4-hydroxy-L-proline + succinate + CO2	-	?

Synonyms

Synonyms	Comment	Organism
PHD	-	Homo sapiens
prolyl hydroxylase	-	Homo sapiens

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Release 2023.1 (January 2023)