Activating Compound | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | stimulates if it reaches an equimolar concentration with Fe2+ | Rattus norvegicus | |
8-hydroxyquinoline | stimulates if it reaches an equimolar concentration with Fe2+ | Rattus norvegicus | |
alpha,alpha'-dipyridyl | stimulates if it reaches an equimolar concentration with Fe2+ | Rattus norvegicus | |
catalase | activation | Rattus norvegicus | |
Diethylenetriaminepentaacetic acid | 5fold stimulation at 0.2 mM, equimolar with Fe2+ | Rattus norvegicus | |
EDTA | 1.4fold stimulation at 0.2 mM, equimolar with Fe2+ | Rattus norvegicus | |
glycoletherdiamine tetraacetic acid | 1.4fold stimulation at 0.2 mM, equimolar with Fe2+, and 2.8fold stimulation at 1 mM | Rattus norvegicus | |
N-Hydroxyethylenediaminetriacetic acid | 5fold stimulation at 0.2 mM, equimolar with Fe2+ | Rattus norvegicus | |
nitrilotriacetic acid | 6fold stimulation at 0.2 mM, equimolar with Fe2+, and 7.6fold stimulation at 1 mM | Rattus norvegicus | |
nucleoside triphosphates | stimulate | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | inhibits at a concentration higher than the Fe2+ concentration in the reaction mixture | Rattus norvegicus | |
2,2'-dipyridyl | inhibits at a concentration higher than the Fe2+ concentration in the reaction mixture | Rattus norvegicus | |
8-hydroxyquinoline | inhibits at a concentration higher than the Fe2+ concentration in the reaction mixture | Rattus norvegicus | |
Diethylenetriaminepentaacetic acid | inhibits at a concentration higher than the Fe2+ concentration in the reaction mixture | Rattus norvegicus | |
EDTA | inhibits at a concentration higher than the Fe2+ concentration in the reaction mixture | Rattus norvegicus | |
N-Hydroxyethylenediaminetriacetic acid | inhibits at a concentration higher than the Fe2+ concentration in the reaction mixture | Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
using ammonium sulfate fractionation and affinity chromatography | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fetus | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
procollagen L-proline + 2-oxoglutarate + O2 | - |
Rattus norvegicus | procollagen trans-4-hydroxy-L-proline + succinate + CO2 | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
2-oxoglutarate | - |
Rattus norvegicus |