Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dichlorochromopyrrolate + 4 O2 + 4 NADH + 4 H+ | Streptomyces longisporoflavus | - |
dichloroarcyriaflavin A + 2 CO2 + 6 H2O + 4 NAD+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces longisporoflavus | Q06IS2 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dichlorochromopyrrolate + 4 O2 + 4 NADH + 4 H+ | - |
Streptomyces longisporoflavus | dichloroarcyriaflavin A + 2 CO2 + 6 H2O + 4 NAD+ | - |
? | |
dichlorochromopyrrolate + 4 O2 + 4 NADH + 4 H+ | StaP/RebP is simply responsible for the two-electron intramolecular aryl-aryl coupling of dichlorochromopyrrolate to give the six-ring intermediate 5,7-dicarboxy-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole with all subsequent steps occurring nonenzymatically in solution. The study on the nonenzymatic steps following StaP-mediated aryl-aryl bond formation corroborates the proposed role of RebC (and by extension StaC) in intercepting and redirecting intermediates en route to the aglycones, K252c, 7-hydroxy-K252c, and arcyriaflavin A | Streptomyces longisporoflavus | dichloroarcyriaflavin A + 2 CO2 + 6 H2O + 4 NAD+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
StaP | - |
Streptomyces longisporoflavus |