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Literature summary for 1.13.11.8 extracted from

  • Kamimura, N.; Aoyama, T.; Yoshida, R.; Takahashi, K.; Kasai, D.; Abe, T.; Mase, K.; Katayama, Y.; Fukuda, M.; Masai, E.
    Characterization of the protocatechuate 4,5-cleavage pathway operon in Comamonas sp. strain E6 and discovery of a novel pathway gene (2010), Appl. Environ. Microbiol., 76, 8093-8101.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.13.11.8

Cloned(Commentary)

Cloned (Comment) Organism
gene organization of the PCA45 pathway genes in strain E6, overview. Identification of the pmd promoter region, the transcription start site of the pmd operon is a thymine 167 nt upstream of the pmdU start codon, overview Comamonas sp.

Organism

Organism UniProt Comment Textmining
Comamonas sp.
-
 a phthalate-degrading bacterium, gene pmdB encodes for the beta-subunit of PCA 4,5-dioxygenase, and harboring of another PCA 4,5-dioxygenase gene, pmdAIIBII
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Comamonas sp. E6
-
 a phthalate-degrading bacterium, gene pmdB encodes for the beta-subunit of PCA 4,5-dioxygenase, and harboring of another PCA 4,5-dioxygenase gene, pmdAIIBII
-

Synonyms

Synonyms Comment Organism
PCA 4,5-dioxygenase
-
 Comamonas sp.

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Comamonas sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
 assay at Comamonas sp.

Expression

Organism Comment Expression
Comamonas sp. the enzyme is induced by protocatechuate up

General Information

General Information Comment Organism
metabolism catabolic pathway for protocatechuate in strain E6 and gene organization of the PCA45 pathway genes, overview Comamonas sp.
additional information PCA 4,5-dioxygenase is essential for growth of strain E6 on protocatechuate, disruption of pmdB in E6, which code for the beta-subunit of PCA 4,5-dioxygenase results in a growth defect on protocatechuate, while inactivation of pmdBII does not affect the growth Comamonas sp.