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Literature summary for 1.13.11.63 extracted from

  • Yan, W.; Jang, G.F.; Haeseleer, F.; Esumi, N.; Chang, J.; Kerrigan, M.; Campochiaro, M.; Campochiaro, P.; Palczewski, K.; Zack, D.J.
    Cloning and characterization of a human beta,beta-carotene-15,15'-dioxygenase that is highly expressed in the retinal pigment epithelium (2001), Genomics, 72, 193-202.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
baculovurus expressed Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
beta-carotene + O2 Homo sapiens enzyme plays an important role in retinoid synthesis. BCDO may also be a candidate gene for retinal degenerative disease retinal
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9HAY6
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-
kidney
-
 Homo sapiens
-
liver
-
 Homo sapiens
-
retina enzyme is highly expressed in retinal pigment epithelium Homo sapiens
-
stomach
-
 Homo sapiens
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testis
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-carotene + O2 enzyme plays an important role in retinoid synthesis. BCDO may also be a candidate gene for retinal degenerative disease Homo sapiens retinal
-
 ?