Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
linoleate + O2 | Beta vulgaris | regiospecificity of Nb-9-LOX, overview | (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Beta vulgaris | - |
ssp. vulgaris | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
root | - |
Beta vulgaris | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
linoleate + O2 | regiospecificity of Nb-9-LOX, overview | Beta vulgaris | (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
9-lipoxygenase | - |
Beta vulgaris |
linoleate 9-lipoxygenase | - |
Beta vulgaris |
General Information | Comment | Organism |
---|---|---|
metabolism | 9-lipoxygenase-generated fatty acid hydroperoxides are converted into specific trihydroxy acids by the EAS-epoxide hydrolase pathway in the beetroot. The linolenic acid-derived hydroperoxide 9(S)-hydroperoxy-10(E),12(Z),15(Z)-octadecatrienoic acid is converted into 9(S),12(S),13(S)-trihydroxy-10(E),15(Z)-octadecadienoic acid (fulgidic acid). On the other hand, the 13-lipoxygenase-generated hydroperoxides of linoleic or linolenic acids fail to produce significant amounts of trihydroxy acids. Short-time incubation of 9(S)-hydroperoxy-10(E),12(Z)-octadecadienoic acid affords the epoxy alcohol 12(R),13(S)-epoxy-9(S)-hydroxy-10(E)-octadecenoic acid as the main product indicating the sequence 9-hydroperoxide to epoxy alcohol to trihydroxy acid catalyzed by epoxy alcohol synthase and epoxide hydrolase activities, respectively | Beta vulgaris |