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Literature summary for 1.13.11.5 extracted from

  • Schmidt, S.R.; Gehrig, A.; Koehler, M.R.; Schmid, M.; Muller, C.R.; Kress, W.
    Cloning of the homogentisate 1,2-dioxygenase gene, the key enzyme of alkaptonuria in mouse (1997), Mamm. Genome, 8, 168-171.
    View publication on PubMed
Search for more literature for 1.13.11.5

Application

Application Comment Organism
medicine HGO gene is responsible for alkaptonuria Mus musculus

Cloned(Commentary)

Cloned (Comment) Organism
complete HGO cDNA, encoding for a 50 kDa protein, is cloned and sequenced Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
49000
-
 x * 49000, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
homogentisate + O2 Mus musculus homogentisate catabolism 4-maleylacetoacetate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
brain expression of HGO gene Mus musculus
-
heart expression of HGO gene Mus musculus
-
kidney expression of HGO gene Mus musculus
-
liver
-
 Mus musculus
-
lung expression of HGO gene Mus musculus
-
muscle expression of HGO gene Mus musculus
-
pancreas expression of HGO gene Mus musculus
-
placenta expression of HGO gene Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
homogentisate + O2
-
 Mus musculus 4-maleylacetoacetate
-
 ?
homogentisate + O2 homogentisate catabolism Mus musculus 4-maleylacetoacetate
-
 ?

Subunits

Subunits Comment Organism
? x * 49000, SDS-PAGE Mus musculus