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Literature summary for 1.13.11.5 extracted from

  • Durand, R.; Zenk, M.H.
    Enzymes of the homogentisate ring-cleavage pathway in cell suspension cultures of higher plants (1974), FEBS Lett., 39, 218-220.
    View publication on PubMed
Search for more literature for 1.13.11.5

Inhibitors

Inhibitors Comment Organism Structure
2,2'-dipyridyl 5 mM, complete inhibition Drosophyllum lusitanicum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
homogentisate + O2 Phaseolus vulgaris homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate 4-maleylacetoacetate
-
 ?
homogentisate + O2 Glycine max homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate 4-maleylacetoacetate
-
 ?
homogentisate + O2 Daucus carota homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate 4-maleylacetoacetate
-
 ?
homogentisate + O2 Nicotiana sylvestris homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate 4-maleylacetoacetate
-
 ?
homogentisate + O2 Ruta graveolens homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate 4-maleylacetoacetate
-
 ?
homogentisate + O2 Melilotus albus homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate 4-maleylacetoacetate
-
 ?
homogentisate + O2 Coleus scutellarioides homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate 4-maleylacetoacetate
-
 ?
homogentisate + O2 Agrostemma githago homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate 4-maleylacetoacetate
-
 ?
homogentisate + O2 Agave toumeyana homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate 4-maleylacetoacetate
-
 ?
homogentisate + O2 Drosophyllum lusitanicum homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate 4-maleylacetoacetate
-
 ?
homogentisate + O2 Pimpinella anisum homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate 4-maleylacetoacetate
-
 ?

Organism

Organism UniProt Comment Textmining
Agave toumeyana
-
-
-
Agrostemma githago
-
-
-
Coleus scutellarioides
-
-
-
Daucus carota
-
-
-
Drosophyllum lusitanicum
-
-
-
Glycine max
-
-
-
Melilotus albus
-
-
-
Nicotiana sylvestris
-
-
-
Phaseolus vulgaris
-
 var. nanus
-
Pimpinella anisum
-
-
-
Ruta graveolens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
190fold purification Drosophyllum lusitanicum
partial purification Phaseolus vulgaris
partial purification Glycine max
partial purification Daucus carota
partial purification Nicotiana sylvestris
partial purification Ruta graveolens
partial purification Melilotus albus
partial purification Coleus scutellarioides
partial purification Agrostemma githago
partial purification Agave toumeyana
partial purification Pimpinella anisum

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Drosophyllum lusitanicum
0.125
-
-
 Melilotus albus
0.17
-
-
 Pimpinella anisum
0.25
-
-
 Daucus carota
0.39
-
-
 Ruta graveolens
0.405
-
-
 Agrostemma githago
0.495
-
-
 Glycine max
0.515
-
-
 Phaseolus vulgaris
0.625
-
-
 Agave toumeyana
1.16
-
-
 Nicotiana sylvestris
2.59
-
-
 Coleus scutellarioides

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
homogentisate + O2
-
 Phaseolus vulgaris 4-maleylacetoacetate
-
 ?
homogentisate + O2
-
 Glycine max 4-maleylacetoacetate
-
 ?
homogentisate + O2
-
 Daucus carota 4-maleylacetoacetate
-
 ?
homogentisate + O2
-
 Nicotiana sylvestris 4-maleylacetoacetate
-
 ?
homogentisate + O2
-
 Ruta graveolens 4-maleylacetoacetate
-
 ?
homogentisate + O2
-
 Melilotus albus 4-maleylacetoacetate
-
 ?
homogentisate + O2
-
 Coleus scutellarioides 4-maleylacetoacetate
-
 ?
homogentisate + O2
-
 Agrostemma githago 4-maleylacetoacetate
-
 ?
homogentisate + O2
-
 Agave toumeyana 4-maleylacetoacetate
-
 ?
homogentisate + O2
-
 Drosophyllum lusitanicum 4-maleylacetoacetate
-
 ?
homogentisate + O2
-
 Pimpinella anisum 4-maleylacetoacetate
-
 ?
homogentisate + O2 homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate Phaseolus vulgaris 4-maleylacetoacetate
-
 ?
homogentisate + O2 homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate Glycine max 4-maleylacetoacetate
-
 ?
homogentisate + O2 homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate Daucus carota 4-maleylacetoacetate
-
 ?
homogentisate + O2 homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate Nicotiana sylvestris 4-maleylacetoacetate
-
 ?
homogentisate + O2 homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate Ruta graveolens 4-maleylacetoacetate
-
 ?
homogentisate + O2 homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate Melilotus albus 4-maleylacetoacetate
-
 ?
homogentisate + O2 homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate Coleus scutellarioides 4-maleylacetoacetate
-
 ?
homogentisate + O2 homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate Agrostemma githago 4-maleylacetoacetate
-
 ?
homogentisate + O2 homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate Agave toumeyana 4-maleylacetoacetate
-
 ?
homogentisate + O2 homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate Drosophyllum lusitanicum 4-maleylacetoacetate
-
 ?
homogentisate + O2 homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate Pimpinella anisum 4-maleylacetoacetate
-
 ?