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Literature summary for 1.13.11.34 extracted from

  • Steinbrink, S.D.; Pergola, C.; Buehring, U.; George, S.; Metzner, J.; Fischer, A.S.; Haefner, A.K.; Wisniewska, J.M.; Geisslinger, G.; Werz, O.; Steinhilber, D.; Maier, T.J.
    Sulindac sulfide suppresses 5-lipoxygenase at clinically relevant concentrations (2010), Cell. Mol. Life Sci., 67, 797-806.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information sulindac sulfone and sulindac do not inhibit 5-LO Homo sapiens
sulindac sulfide 5-LO-selective inhibitor Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood
-
Homo sapiens
-
blood plasma
-
Homo sapiens
-
polymorphonuclear leukocyte
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
5-lipoxygenase
-
Homo sapiens
5-LO
-
Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.02
-
pH and temperature not specified in the publication Homo sapiens sulindac sulfide