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Literature summary for 1.13.11.34 extracted from
- Dihydroxydocosahexaenoic acids of the neuroprotectin D family: synthesis, structure, and inhibition of human 5-lipoxygenase (2006), J. Lipid Res., 47, 2462-2474.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 10,17(S)-dihydroxydocosahexaenoic acid | IC50: 0.017 mM | Homo sapiens |  |
| 7,17(S)-dihydroxydocosahexaenoic acid | IC50: 0.007 mM | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| arachidonate + O2 | - |
Homo sapiens | (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 5LOX-1 | - |
Homo sapiens |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.007 | - |
IC50: 0.007 mM | Homo sapiens | 7,17(S)-dihydroxydocosahexaenoic acid | |
| 0.017 | - |
IC50: 0.017 mM | Homo sapiens | 10,17(S)-dihydroxydocosahexaenoic acid | |
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