Application | Comment | Organism |
---|---|---|
medicine | the 12/15-LOX metabolic pathway is increased and correlates with an oxidative imbalance in the Alzheimers disease brain, implying that this enzyme might contribute to the pathogenesis of this neurodegenerative disorder. Thus, drugs that specifically reduce or block the 12/15-LOX metabolic pathway activation may warrant consideration as potential therapeutic interventions for Alzheimers disease | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the 12/15-LOX metabolic pathway is increased and correlates with an oxidative imbalance in the Alzheimers disease brain, implying that this enzyme might contribute to the pathogenesis of this neurodegenerative disorder | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | the 12/15-LOX metabolic pathway is increased and correlates with an oxidative imbalance in the Alzheimers disease brain, implying that this enzyme might contribute to the pathogenesis of this neurodegenerative disorder | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the 12/15-LOX metabolic pathway is increased and correlates with an oxidative imbalance in the Alzheimers disease brain, implying that this enzyme might contribute to the pathogenesis of this neurodegenerative disorder | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
12/15-lipoxygenase | - |
Homo sapiens |
12/15-LOX | - |
Homo sapiens |