Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Bos taurus | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leukocyte | - |
Bos taurus | - |
platelet | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0003 | - |
enzyme from platelet | Bos taurus |
0.0011 | - |
enzyme from leukocyte | Bos taurus |
Storage Stability | Organism |
---|---|
-80°C, stable for at least 1 week | Bos taurus |
4°C, half-life of leukocyte enzyme is 2 h, half-life of platelet enzyme is 70 h | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
11,14,17-eicosatrienoic acid + O2 | leukocyte enzyme: 28% of the activity with arachidonic acid, platelet enzyme: less than 2% of the activity with arachidonic acid | Bos taurus | ? | - |
? | |
11,14-eicosadienoic acid + O2 | leukocyte enzyme: 15% of the activity with arachidonic acid, platelet enzyme: less than 2% of the activity with arachidonic acid | Bos taurus | ? | - |
? | |
15(S)-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoic acid + O2 | leukocyte enzyme: 18% of the activity with arachidonic acid, platelet enzyme: 6% of the activity with arachidonic acid | Bos taurus | additional information | - |
? | |
4,7,10,13,16,19-docosahexaenoic acid + O2 | leukocyte enzyme: 92% of the activity with arachidonic acid, platelet enzyme: 7% of the activity with arachidonic acid | Bos taurus | ? | - |
? | |
5(S)-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid + O2 | leukocyte enzyme: 15% of the activity with arachidonic acid, platelet enzyme: less than 2% of the activity with arachidonic acid | Bos taurus | 5,12-(5S,12S)-dihydroxy-6E,8Z,10E,14Z-eicosatetraenoic acid + 5,12-(5S,15S)-dihydroxy-6E,8Z,11Z,13E-eicosatetraenoic acid | - |
? | |
5,8,11,14,17-eicosapentaenoic acid + O2 | leukocyte enzyme: 73% of the activity with arachidonic acid, platelet enzyme: less than 94% of the activity with arachidonic acid | Bos taurus | 12-hydroxy-5,8,10,14,17-eicosapentaenoic acid | - |
? | |
8,11,14-eicosatrienoic acid + O2 | leukocyte enzyme: 78% of the activity with arachidonic acid, platelet enzyme: 7% of the activity with arachidonic acid | Bos taurus | 12-hydroxyeicosatrienoic acid | - |
? | |
alpha-linolenic acid + O2 | leukocyte enzyme: 17% of the activity with arachidonic acid, platelet enzyme: less than 2% of the activity with arachidonic acid | Bos taurus | ? | - |
? | |
arachidonate + O2 | i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid | Bos taurus | (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate | - |
? | |
gamma-linolenic acid + O2 | leukocyte enzyme: 32% of the activity with arachidonic acid, platelet enzyme: less than 2% of the activity with arachidonic acid | Bos taurus | 10-hydroxy-octadeca-6Z,8E,12Z-trienoic acid | - |
? | |
linoleic acid + O2 | leukocyte enzyme: 11% of the activity with arachidonic acid, platelet enzyme: less than 2% of the activity with arachidonic acid | Bos taurus | 13(S)-hydroperoxy-9Z,11E-octadecadienoic acid | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 8 | - |
Bos taurus |