Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2E)-3-(3,4-dimethoxyphenyl)-N-hydroxyprop-2-enamide | over 90% inhibition at 0.2 mM | Rhodococcus jostii | |
(2E)-N-hydroxy-3-(4-methoxyphenyl)prop-2-enamide | over 90% inhibition at 0.2 mM | Rhodococcus jostii | |
2-(2H-1,3-benzodioxol-5-yl)-N-[(4-fluorophenyl)methyl]-N-hydroxyacetamide | 60% inhibition at 0.2 mM | Rhodococcus jostii | |
3-(3,4-dimethoxyphenyl)-N-hydroxy-N-octylpropanamide | 57% inhibition at 0.2 mM | Rhodococcus jostii | |
3-(3,4-dimethoxyphenyl)-N-hydroxypropanamide | 60% inhibition at 0.2 mM | Rhodococcus jostii | |
additional information | poor inhibition by N-hydroxy-3-(4-methoxyphenyl)propanamide at 0.2 mM | Rhodococcus jostii |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3,4-dihydroxybenzoate + O2 | Rhodococcus jostii | - |
3-carboxy-cis,cis-muconate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rhodococcus jostii | Q0SH27 AND Q0SH26 | beta- and alpha-subunit | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3,4-dihydroxybenzoate + O2 | - |
Rhodococcus jostii | 3-carboxy-cis,cis-muconate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
3,4-PCD | - |
Rhodococcus jostii |
protocatechuate 3,4-dioxygenase | - |
Rhodococcus jostii |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rhodococcus jostii |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Rhodococcus jostii |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.015 | - |
pH 7.5, 37°C | Rhodococcus jostii | (2E)-N-hydroxy-3-(4-methoxyphenyl)prop-2-enamide | |
0.02 | - |
pH 7.5, 37°C | Rhodococcus jostii | (2E)-3-(3,4-dimethoxyphenyl)-N-hydroxyprop-2-enamide | |
0.16 | - |
pH 7.5, 37°C | Rhodococcus jostii | 3-(3,4-dimethoxyphenyl)-N-hydroxypropanamide |