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Literature summary for 1.12.99.6 extracted from
- Role of the NiFe hydrogenase Hya in oxidative stress defense in Geobacter sulfurreducens (2012), J. Bacteriol., 194, 2248-2253.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Geobacter sulfurreducens | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Hya | - |
Geobacter sulfurreducens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | isoform Hya is necessary for growth after exposure to oxidative stress when hydrogen or a highly limiting concentration of acetate is the electron source. The beneficial impact of Hya on growth is dependent on the presence of H2 in the atmosphere. A Hya-deficient strain is more sensitive to the presence of superoxide or hydrogen peroxide. Hya is also required to safeguard Hyb hydrogen oxidation activity after exposure to O2. Isoform Hya is more resistant to oxidative stress than Hyb. Overexpression of Hya also results in the creation of a recombinant strain better fitted for exposure to oxidative stress than wild-type | Geobacter sulfurreducens |
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Release 2023.1 (January 2023)
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