Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | cytoplasmic granule | Homo sapiens | 5737 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Cl- + H2O2 + H+ | Homo sapiens | - |
HClO + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neutrophil | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Cl- + H2O2 + H+ | - |
Homo sapiens | HClO + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
donor:H2O2 oxidoreductase | - |
Homo sapiens |
MPO | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | upon the action of the MPO-H2O2-chloride system, two of the major functional activities of kininogens: the susceptibility of high-molecular mass kininogen and low-molecular mass kininogen to kinin-forming action of kallikreins and the prekallikrein-binding capability of high-molecular mass kininogen, are dramatically impaired | Homo sapiens |