Inhibitors | Comment | Organism | Structure |
---|---|---|---|
azide | uncompetitive; uncompetitive inhibition, inhibition constant: 50 nM | Curvularia inaequalis | |
hydrazine | uncompetitive; uncompetitive inhibition, inhibition constant: 0.3 mM | Curvularia inaequalis | |
hydroxylamine | competitive and uncompetitive inhibition; inhibits rVCPO both competitively and uncompetitively. The competitive inhibition constant: 0.04 mM, uncompetitive inhibition 0.08 mM | Curvularia inaequalis | |
phosphate | substitution of vanadate in the active site by phosphate leads to inactivation of the enzyme. Presence of H2O2 prevents inactivation by phosphate; substitution of vanadate in the active site by phosphate leads to inactivation. Presence of H2O2 prevents the inactivation | Curvularia inaequalis |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Vanadium | substitution of vanadate in the active site by phosphate leads to inactivation of the enzyme. Pervanadate is bound much more strongly to the enzyme than vanadate | Curvularia inaequalis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Curvularia inaequalis | P49053 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Br- + H2O2 + 1,1-dimethyl-4-chloro-3,5-cyclohexanedione | i.e. monochlorodimedone | Curvularia inaequalis | ? | - |
? | |
Cl- + H2O2 + 1,1-dimethyl-4-chloro-3,5-cyclohexanedione | i.e. monochlorodimedone | Curvularia inaequalis | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
vanadium chloroperoxidase | - |
Curvularia inaequalis |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.04 | - |
hydroxylamine | competitive inhibition constant | Curvularia inaequalis | |
0.08 | - |
hydroxylamine | uncompetitive inhibition constant | Curvularia inaequalis | |
0.35 | - |
hydrazine | - |
Curvularia inaequalis |