Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.11.1.9 extracted from

  • Wendel, A.
    Glutathione peroxidase (1981), Methods Enzymol., 77, 325-333.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
-
Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
Ag+
-
Bos taurus
Chloroacetate
-
Bos taurus
iodoacetate
-
Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
21900
-
alpha4, 4 * 21900, nucleotide sequence, SDS-PAGE Bos taurus
75000 85500 gel filtration Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glutathione + ROOH Mammalia cumene hydroperoxide glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH Bos taurus cumene hydroperoxide glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH Mammalia ethyl hydroperoxide glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH Bos taurus ethyl hydroperoxide glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH Bos taurus cholesterol 7beta-hydroperoxide glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH Mammalia peroxidized DNA glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH Bos taurus peroxidized DNA glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH Bos taurus pregnenolone 17alpha-hydroperoxide glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH Mammalia thymine hydroperoxide glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH Bos taurus thymine hydroperoxide glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH Mammalia highly specific for glutathione glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH Bos taurus highly specific for glutathione glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH Mammalia linoleic acid hydroperoxide glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH Bos taurus linoleic acid hydroperoxide glutathione disulfide + ROH + H2O
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Mammalia
-
-
-
no activity in plants
-
-
-

Oxidation Stability

Oxidation Stability Organism
autooxidation, reactivation by glutathione Mammalia
autooxidation, reactivation by glutathione Bos taurus

Purification (Commentary)

Purification (Comment) Organism
-
Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
blood
-
Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutathione + ROOH cumene hydroperoxide Mammalia glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH cumene hydroperoxide Bos taurus glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH ethyl hydroperoxide Mammalia glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH ethyl hydroperoxide Bos taurus glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH cholesterol 7beta-hydroperoxide Bos taurus glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH peroxidized DNA Mammalia glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH peroxidized DNA Bos taurus glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH pregnenolone 17alpha-hydroperoxide Bos taurus glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH thymine hydroperoxide Mammalia glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH thymine hydroperoxide Bos taurus glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH highly specific for glutathione Mammalia glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH highly specific for glutathione Bos taurus glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH linoleic acid hydroperoxide Mammalia glutathione disulfide + ROH + H2O
-
?
glutathione + ROOH linoleic acid hydroperoxide Bos taurus glutathione disulfide + ROH + H2O
-
?

Subunits

Subunits Comment Organism
homotetramer
-
Mammalia
homotetramer alpha4, 4 * 21900, nucleotide sequence, SDS-PAGE Bos taurus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
42
-
-
Bos taurus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.8
-
-
Bos taurus

pH Stability

pH Stability pH Stability Maximum Comment Organism
7 10
-
Bos taurus