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Literature summary for 1.11.1.8 extracted from

  • Gardas, A.; Lewartowska, A.; Sutton, B.J.; Pasieka, Z.; McGregor, M.; Banga, J.P.
    Human thyroid peroxidase (TPO) isoforms, TPO-1 and TPO-2: Analysis of protein expression in Graves' thyroid tissue (1997), J. Clin. Endocrinol. Metab., 82, 3752-3756.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Homo sapiens
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
100000
-
SDS-PAGE, isoform 2 Homo sapiens
105000
-
SDS-PAGE, isoform 1 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
iodide + H2O2 Homo sapiens biosynthesis of thyroid hormones iodine + H2O
-
?
iodide + H2O2 Homo sapiens autoantigenin autoimmune thyroid disease iodine + H2O
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
two isoforms found
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
thyroid gland
-
Homo sapiens
-

Storage Stability

Storage Stability Organism
-70°C, 50 mM Tris-HCl, 0.15 M NaCl, pH 8.5, 0.1% deoxycholate Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
iodide + H2O2
-
Homo sapiens iodine + H2O
-
?
iodide + H2O2 biosynthesis of thyroid hormones Homo sapiens iodine + H2O
-
?
iodide + H2O2 autoantigenin autoimmune thyroid disease Homo sapiens iodine + H2O
-
?