Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-Methyl-2-mercaptoimidazole | competitive with iodide | Sus scrofa | |
azide | very effective | Sus scrofa | |
glutathione | - |
Sus scrofa | |
Iodide | above 0.1 mM at pH 5, no inhibition at pH 7 | Sus scrofa | |
p-Aminobenzoic acid | - |
Sus scrofa | |
resorcinol | - |
Sus scrofa | |
sulfathiazole | - |
Sus scrofa | |
thiocyanate | competitive with iodide | Sus scrofa | |
thiouracil | - |
Sus scrofa | |
Thiourea | - |
Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.25 | - |
I- | - |
Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
64000 | - |
gel filtration, analytical ultracentrifugation | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
iodide + H2O2 | Sus scrofa | iodination and coupling reactions of proteins | iodine + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
pig, female | - |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
intestine | - |
Sus scrofa | - |
lymphoid tissue | - |
Sus scrofa | - |
additional information | traces of activity in liver, kidney, heart, brain, ovary and muscle | Sus scrofa | - |
salivary gland | - |
Sus scrofa | - |
spleen | - |
Sus scrofa | - |
thyroid gland | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
32 | - |
purified enzyme | Sus scrofa |
Storage Stability | Organism |
---|---|
-20°C, 6-12 months, no loss of activity | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
iodide + H2O2 | highest activity if coupled with glucose-glucose oxidase reaction for H2O2 production | Sus scrofa | iodine + H2O | - |
? | |
iodide + H2O2 | iodination and coupling reactions of proteins | Sus scrofa | iodine + H2O | - |
? |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5 | 7 | activity independent of pH | Sus scrofa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | - |
Sus scrofa |