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Literature summary for 1.11.1.7 extracted from

  • Takashima, E.; Konishi, K.
    Characterization of a quinol peroxidase mutant in Aggregatibacter actinomycetemcomitans (2008), FEMS Microbiol. Lett., 286, 66-70.
    View publication on PubMed
Search for more literature for 1.11.1.7

Application

Application Comment Organism
medicine QPO is a potential drug target to inhibit the expression of leukotoxin LtxA from Aggregatibacter actinomycetemcomitans for the treatment and prevention of localized aggressive periodontitis Aggregatibacter actinomycetemcomitans

Protein Variants

Protein Variants Comment Organism
additional information the QPO null mutant shows an oxidative stress phenotype, suggesting that QPO plays a certain role in scavenging endogenously generated reactive oxygen species Aggregatibacter actinomycetemcomitans

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
53600
-
 SDS-PAGE Aggregatibacter actinomycetemcomitans

Organism

Organism UniProt Comment Textmining
Aggregatibacter actinomycetemcomitans A2A1C5
-
-
Aggregatibacter actinomycetemcomitans IDH781 A2A1C5
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information QPO catalyzes the reduction of H2O2 but not tert-butyl hydroperoxide and cumene hydroperoxide Aggregatibacter actinomycetemcomitans ?
-
 ?
additional information QPO catalyzes the reduction of H2O2 but not tert-butyl hydroperoxide and cumene hydroperoxide Aggregatibacter actinomycetemcomitans IDH781 ?
-
 ?
ubiquinol-1 + H2O2
-
 Aggregatibacter actinomycetemcomitans ? + H2O
-
 ?
ubiquinol-1 + H2O2
-
 Aggregatibacter actinomycetemcomitans IDH781 ? + H2O
-
 ?

Synonyms

Synonyms Comment Organism
QPO
-
 Aggregatibacter actinomycetemcomitans
quinol peroxidase
-
 Aggregatibacter actinomycetemcomitans