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Literature summary for 1.11.1.5 extracted from

  • Charoensuk, K.; Irie, A.; Lertwattanasakul, N.; Sootsuwan, K.; Thanonkeo, P.; Yamada, M.
    Physiological importance of cytochrome c peroxidase in ethanologenic thermotolerant Zymomonas mobilis (2011), J. Mol. Microbiol. Biotechnol., 20, 70-82.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information construction of disruption knockout mutant DELTAZmcytC, phenotype, overview Zymomonas mobilis

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Zymomonas mobilis 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Iron heme enzyme Zymomonas mobilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 ferrocytochrome c + H2O2 Zymomonas mobilis
-
2 ferricytochrome c + 2 H2O
-
?

Organism

Organism UniProt Comment Textmining
Zymomonas mobilis Q5NNF0 gene ZmcytC
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 ferrocytochrome c + H2O2
-
Zymomonas mobilis 2 ferricytochrome c + 2 H2O
-
?

Synonyms

Synonyms Comment Organism
CCP
-
Zymomonas mobilis
CytC
-
Zymomonas mobilis
cytochrome c peroxidase
-
Zymomonas mobilis

Cofactor

Cofactor Comment Organism Structure
heme the enzyme bears three heme c-binding motifs Zymomonas mobilis

General Information

General Information Comment Organism
malfunction an enzyme knockout mutant DELTAZmcytC exhibits filamentous shapes and reduction in growth under a shaking condition at a high temperature compared to the parental strain and became hypersensitive to exogenous H2O2. Under the same condition, the mutation causes increased expression of genes for three other antioxidant enzymes. Peroxidase activity almost abolished in mutant DELTA ZmcytC. The enzyme knockout mutant strain shows activity with ubiquinol-1 as a substrate but not with reduced horse heart cytochrome c, and it shows antimycin A-sensitive NADH oxidase activity Zymomonas mobilis
physiological function involvement of ZmCytC in the aerobic respiratory chain via the cytochrome bc1 complex in addition to the previously proposed direct interaction with ubiquinol and its contribution to protection against oxidative stress Zymomonas mobilis