Crystallization (Comment) | Organism |
---|---|
crystal structures of holoenzyme and the complex with fosfomycin are determined and reveal a two-domain combination and Zn2+ in the active site | Streptomyces wedmorensis |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | the recombinant enzyme is active, when reconstituted with Zn2+ or Fe2+ | Streptomyces wedmorensis | |
Zn2+ | the recombinant enzyme is active, when reconstituted with Zn2+ or Fe2+ | Streptomyces wedmorensis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces wedmorensis | Q56185 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Streptomyces wedmorensis |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
(S)-2-hydroxypropylphosphonate + H2O2 = (1R,2S)-1,2-epoxypropylphosphonate + 2 H2O | a straightforward epoxidase mechanism is proposed that depends on the Lewis acid properties of divalent cations and the redox properties of FMN | Streptomyces wedmorensis |
Synonyms | Comment | Organism |
---|---|---|
HppE | - |
Streptomyces wedmorensis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FMN | a straightforward epoxidase mechanism is proposed that depends on the Lewis acid properties of divalent cations and the redox properties of FMN | Streptomyces wedmorensis |