Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
20000 | - |
SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
ammonium sulfate precipitation, DEAE-Sepharose column chromatography, Sephadex G-50 gel filtration, and HiTrap SP column chromatography | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
testis | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.051 | - |
enzyme from tissue lysate, using L-alpha-phosphatidylcholine hydroperoxide as peroxide substrate, at 37°C | Rattus norvegicus |
21.5 | - |
enzyme after 422fold purification, using L-alpha-phosphatidylcholine hydroperoxide as peroxide substrate, at 37°C | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + 3beta-hydroxycholest-5-ene-7alpha-hydroperoxide | - |
Rattus norvegicus | cholest-5-ene-3beta,7alpha-diol + ? | - |
? | |
glutathione + cumene hydroperoxide | - |
Rattus norvegicus | ? | - |
? | |
glutathione + L-alpha-phosphatidylcholine hydroperoxide | - |
Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GPx4 | - |
Rattus norvegicus |
phospholipid hydroperoxide glutathione peroxidase | - |
Rattus norvegicus |
type-4 glutathione peroxidase | - |
Rattus norvegicus |