Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
20000 | - |
gel filtration | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + lipid hydroperoxide | Sus scrofa | protection of biomembranes against oxidative damage | glutathione disulfide + lipid + H2O | - |
? | |
additional information | Sus scrofa | enzyme inhibits lipid peroxidation, which is induced by Fe3+-triethylenetetramine complex, NADPH and ascorbate in presence of glutathione, therefore a physiological amount of alpha-tocopherol, vitamin E, is necessary in the membranes | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Sus scrofa | - |
liver | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.9 | - |
substrate tert-butyl hydroperoxide | Sus scrofa |
2.2 | - |
substrate phosphatidylcholine | Sus scrofa |
3.8 | - |
substrate cumene hydroperoxide | Sus scrofa |
107 | - |
purified enzyme | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + cumene hydroperoxide | - |
Sus scrofa | ? | - |
? | |
glutathione + L-alpha-phosphatidylcholine hydroperoxide | - |
Sus scrofa | ? | - |
? | |
glutathione + lipid hydroperoxide | - |
Sus scrofa | glutathione disulfide + lipid + H2O | - |
? | |
glutathione + lipid hydroperoxide | protection of biomembranes against oxidative damage | Sus scrofa | glutathione disulfide + lipid + H2O | - |
? | |
glutathione + tert-butyl hydroperoxide | - |
Sus scrofa | ? | - |
? | |
additional information | enzyme inhibits lipid peroxidation, which is induced by Fe3+-triethylenetetramine complex, NADPH and ascorbate in presence of glutathione, therefore a physiological amount of alpha-tocopherol, vitamin E, is necessary in the membranes | Sus scrofa | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 20000, SDS-PAGE | Sus scrofa |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
65 | - |
complete loss of activity after 5 min | Sus scrofa |