Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.11.1.1 extracted from

  • Miller, H.; Poole, L.B.; Claiborne, A.
    Heterogeneity among the flavin-containing NADH peroxidases of group D streptococci. Analysis of the enzyme from Streptococcus faecalis ATCC 9790 (1990), J. Biol. Chem., 265, 9857-9863.
    View publication on PubMed
Search for more literature for 1.11.1.1

Inhibitors

Inhibitors Comment Organism Structure
Ethyl hydroperoxide
-
 Enterococcus faecalis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0025
-
 NADH
-
 Enterococcus faecalis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NADH + H2O2 Enterococcus faecalis elimination of toxic H2O2, regeneration of oxidized pyridine nucleotide which is essential to the strictly fermentative metabolism NAD+ + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Enterococcus faecalis
-
 Enterococcus hirae
-

Purification (Commentary)

Purification (Comment) Organism
-
 Enterococcus faecalis

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
86
-
-
 Enterococcus faecalis

Storage Stability

Storage Stability Organism
-20°C, 50 mM phosphate buffer pH 7.0 Enterococcus faecalis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NADH + H2O2 elimination of toxic H2O2, regeneration of oxidized pyridine nucleotide which is essential to the strictly fermentative metabolism Enterococcus faecalis NAD+ + H2O
-
 ?

pH Stability

pH Stability pH Stability Maximum Comment Organism
5.4
-
 45 min stable Enterococcus faecalis

Cofactor

Cofactor Comment Organism Structure
FAD enzyme contains flavin and non-flavin redox centers Enterococcus faecalis