Activating Compound | Comment | Organism | Structure |
---|---|---|---|
FAD | slight activation | Monocillium spp. |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NADH | apparent inhibition | Monocillium spp. | |
NADPH | apparent inhibition | Monocillium spp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
rifamycin B + O2 | Monocillium spp. | reverse reaction of rifamycin B biosynthesis | rifamycin O + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Monocillium spp. | - |
ATCC 20621 | - |
Purification (Comment) | Organism |
---|---|
ammonium sulfate precipitation, ion-exchange, gel filtration | Monocillium spp. |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
rifamycin B + O2 = rifamycin O + H2O2 | acting on diphenols and related substances as electron donors and on oxygen as an electron acceptor | Monocillium spp. |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
3.19 | - |
- |
Monocillium spp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
p-hydroquinone + O2 | rapid oxidation | Monocillium spp. | ? | - |
? | |
pyrogallol + ? | - |
Monocillium spp. | ? | - |
? | |
rifamycin B + O2 | rapid oxidation | Monocillium spp. | rifamycin O + H2O2 | - |
? | |
rifamycin B + O2 | reverse reaction of rifamycin B biosynthesis | Monocillium spp. | rifamycin O + H2O2 | - |
? | |
rifamycin SV + ? | - |
Monocillium spp. | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | 40 | assay at | Monocillium spp. |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.8 | - |
assay at | Monocillium spp. |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
additional information | enzyme contains no flavins, heme, Cu2+ or other metal ions | Monocillium spp. |