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Literature summary for 1.10.3.11 extracted from
- The cyanide-resistant alternative oxidases from the fungi Pichia stipitis and Neurospora crassa are monomeric and lack regulatory features of the plant enzyme (2000), Arch. Biochem. Biophys., 378, 234-245.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| ADP | - |
Neurospora crassa |  |
| ADP | - |
Scheffersomyces stipitis | |
| GMP | GMP (0.25 mM) is a strong activator | Neurospora crassa | |
| GMP | GMP (0.25 mM) is a strong activator | Scheffersomyces stipitis | |
| additional information | alternative oxidase activity is not stimulated by pyruvate and glyoxylate. Pyruvate does only stimulate activity when succinate is the respiratory substrate but this is not a direct effect on the alternative oxidase | Neurospora crassa | |
| additional information | alternative oxidase activity is not stimulated by pyruvate and glyoxylate. Pyruvate does only stimulate activity when succinate is the respiratory substrate but this is not a direct effect on the alternative oxidase | Scheffersomyces stipitis | |
| pyruvate | - |
Neurospora crassa | |
| pyruvate | - |
Scheffersomyces stipitis | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Neurospora crassa | 5739 | - |
| mitochondrion | - |
Scheffersomyces stipitis | 5739 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 36000 | - |
1 * 36000, SDS-PAGE | Neurospora crassa |
| 36000 | - |
1 * 36000, SDS-PAGE | Scheffersomyces stipitis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Neurospora crassa | - |
- |
- |
| Scheffersomyces stipitis | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| duroquinol + O2 | - |
Neurospora crassa | duroquinone + H2O | - |
? | |
| duroquinol + O2 | - |
Scheffersomyces stipitis | duroquinone + H2O | - |
? | |
| additional information | the enzyme is unable to use NADH as respiratory substrate | Neurospora crassa | ? | - |
? | |
| additional information | the enzyme is unable to use NADH as respiratory substrate | Scheffersomyces stipitis | ? | - |
? | |
| succinate + O2 | - |
Neurospora crassa | ? | - |
? | |
| succinate + O2 | - |
Scheffersomyces stipitis | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 36000, SDS-PAGE | Neurospora crassa |
| monomer | 1 * 36000, SDS-PAGE | Scheffersomyces stipitis |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| cyanide-resistant alternative oxidase | - |
Neurospora crassa |
| cyanide-resistant alternative oxidase | - |
Scheffersomyces stipitis |
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Release 2023.1 (January 2023)
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