Any feedback?
Literature summary for 1.10.3.11 extracted from
- Activation of the plant alternative oxidase by high reduction levels of the Q-pool and pyruvate (1998), Arch. Biochem. Biophys., 355, 262-270.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| dithiothreitol | - |
Glycine max |  |
| dithiothreitol | - |
Arum italicum | |
| pyruvate | AOX is activated when the ubiquinone-pool becomes highly reduced in the presence of pyruvate. The enzyme is not activated when pyruvate is added after a transient high reduction level of the Q-pool, but is when pyruvate is added before the transient reduction. In the presence of pyruvate, NADH and succinate oxidation can stimulate AOX activity by substituting for dithiothreitol | Glycine max | |
| pyruvate | AOX is activated when the ubiquinone-pool becomes highly reduced in the presence of pyruvate. The enzyme is not activated when pyruvate is added after a transient high reduction level of the Q-pool, but is when pyruvate is added before the transient reduction. In the presence of pyruvate, NADH and succinate oxidation can stimulate AOX activity by substituting for dithiothreitol | Arum italicum | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| octyl gallate | - |
Arum italicum | |
| octyl gallate | - |
Glycine max | |
| ubiquinol | AOX is inactivated by its product ubiquinol during catalysis, this inhibition is prevented in the presence of pyruvate. The inhibition can be reversed by a reductive process, achieved by high levels of reduction of the ubiquinone-pool or by dithiothreitol | Arum italicum | |
| ubiquinol | AOX is inactivated by its product ubiquinol during catalysis, this inhibition is prevented in the presence of pyruvate. The inhibition can be reversed by a reductive process, achieved by high levels of reduction of the ubiquinone-pool or by dithiothreitol | Glycine max | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Glycine max | 5739 | - |
| mitochondrion | - |
Arum italicum | 5739 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 35000 | - |
2 * 35000, SDS-PAGE | Glycine max |
| 35000 | - |
2 * 35000, SDS-PAGE | Arum italicum |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arum italicum | - |
- |
- |
| Glycine max | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cotyledon | - |
Glycine max | - |
| flower | - |
Arum italicum | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ubiquinol + O2 | - |
Glycine max | ubiquinone + H2O | - |
? | |
| ubiquinol + O2 | - |
Arum italicum | ubiquinone + H2O | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homodimer | 2 * 35000, SDS-PAGE | Glycine max |
| homodimer | 2 * 35000, SDS-PAGE | Arum italicum |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alternative oxidase | - |
Glycine max |
| alternative oxidase | - |
Arum italicum |
| AOX | - |
Glycine max |
| AOX | - |
Arum italicum |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
