Protein Variants | Comment | Organism |
---|---|---|
A140P | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
A184V | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
A406V | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
A62D | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
C179R | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
E176D | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
E176G | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
E268X | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
E336K | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
G116D | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
G128X | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
G156V | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
G211D | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
G211V | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
G260A | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
G260V | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
G55D | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
G57R | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
H434P | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
H98R | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
H98Y | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
K246N | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
K81E | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
P302L | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
P441E | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
Q197X | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
Q204X | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
R251X | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
R277X | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
R282Q | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
R282W | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
R335X | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
R70X | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
S263L | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
S263X | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
S440Y | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
V296E | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
Y153X | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
Y195C | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
Y301X | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
Y367C | the mutation is associated with L-2-hydroxyglutaric aciduria | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-2-hydroxyglutarate + acceptor | Homo sapiens | - |
2-oxoglutarate + reduced acceptor | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-2-hydroxyglutarate + acceptor | - |
Homo sapiens | 2-oxoglutarate + reduced acceptor | - |
? |
Synonyms | Comment | Organism |
---|---|---|
L-2-hydroxyglutarate dehydrogenase | - |
Homo sapiens |
L2HGDH | - |
Homo sapiens |