Literature summary for 1.1.98.6 extracted from

Kirdis, E.; Jonsson, I.M.; Kubica, M.; Potempa, J.; Josefsson, E.; Masalha, M.; Foster, S.J.; Tarkowski, A.
Ribonucleotide reductase class III, an essential enzyme for the anaerobic growth of Staphylococcus aureus, is a virulence determinant in septic arthritis (2007), Microb. Pathog., 43, 179-188.

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Application

Application	Comment	Organism
medicine	ribonucleotide reductase class III is a virulence determinant in the pathogenesis of staphylococcal arthritis. Mice inoculated with the wild-type strain display significantly more severe arthritis, with significantly more synovitis and destruction of the bone and cartilage versus mice inoculated with a NrdDG mutant strain. The persistence of bacteria in the kidneys is significantly more pronounced in the group inoculated with the wild-type strain	Staphylococcus aureus

Organism

Organism	UniProt	Comment	Textmining
Staphylococcus aureus	A0A0H3KJ34	-	-
Staphylococcus aureus Newman	A0A0H3KJ34	-	-

Synonyms

Synonyms	Comment	Organism
nrdD	-	Staphylococcus aureus

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Release 2023.1 (January 2023)