Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cytochrome c | role of cyt c in activation of glycerol-3-phosphate and succinate oxidation in frozenthawed mitochondria | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Digitonin | strong inhibition, the activity is recovered to 148% of control values by the addition of exogenous synthetic analog of CoQ idebenone, i.e. hydroxydecylubiquinone, and cytochrome c. The compound also strongly activates glycerol-3-phosphate oxidation inhibited by endogenous or added free fatty acids | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial inner membrane | - |
Rattus norvegicus | 5743 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
sn-glycerol 3-phosphate + oxidized coenzyme Q | Rattus norvegicus | - |
glycerone phosphate + reduced coenzyme Q | - |
? | |
sn-glycerol 3-phosphate + oxidized coenzyme Q | Rattus norvegicus Wistar | - |
glycerone phosphate + reduced coenzyme Q | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Rattus norvegicus Wistar | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | very low activity | Rattus norvegicus | - |
thyroid gland | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
sn-glycerol 3-phosphate + oxidized coenzyme Q | - |
Rattus norvegicus | glycerone phosphate + reduced coenzyme Q | - |
? | |
sn-glycerol 3-phosphate + oxidized coenzyme Q | - |
Rattus norvegicus Wistar | glycerone phosphate + reduced coenzyme Q | - |
? |
Synonyms | Comment | Organism |
---|---|---|
flavoprotein-dependent glycerol-3-phosphate dehydrogenase | - |
Rattus norvegicus |
glycerol-3-phosphate oxidoreductase | - |
Rattus norvegicus |
GPDH | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
coenzyme Q | - |
Rattus norvegicus |