KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
4.68 | - |
L-lactate | - |
Rattus sp. |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus sp. | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
88900 | - |
sedimentation equilibrium analysis | Rattus sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
DL-2-hydroxybutyrate + O2 | Rattus sp. | - |
2-oxobutyrate + H2O2 | - |
? | |
DL-2-hydroxycaproate + O2 | Rattus sp. | - |
2-oxocaproate + H2O2 | - |
? | |
DL-2-hydroxyisocaproate + O2 | Rattus sp. | - |
2-oxoisocaproate + H2O2 | - |
? | |
DL-2-hydroxyisovalerate + O2 | Rattus sp. | - |
2-oxoisovalerate + H2O2 | - |
? | |
DL-2-hydroxyvalerate + O2 | Rattus sp. | - |
2-oxovalerate + H2O2 | - |
? | |
L-2-hydroxyisocaproate + O2 | Rattus sp. | - |
2-oxoisocaproate + H2O2 | - |
? | |
L-alanine + O2 | Rattus sp. | low activity | ? + H2O2 | - |
? | |
L-isoleucine + O2 | Rattus sp. | low activity | ? + H2O2 | - |
? | |
L-lactate + O2 | Rattus sp. | - |
pyruvate + H2O2 | - |
? | |
L-leucine + O2 | Rattus sp. | highest activity | ? + H2O2 | - |
? | |
L-methionine + O2 | Rattus sp. | - |
? + H2O2 | - |
? | |
L-phenylalanine + O2 | Rattus sp. | - |
? + H2O2 | - |
? | |
L-tryptophan + O2 | Rattus sp. | - |
? + H2O2 | - |
? | |
L-tyrosine + O2 | Rattus sp. | - |
? + H2O2 | - |
? | |
L-valine + O2 | Rattus sp. | low activity | ? + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus sp. | - |
- |
- |
Purification (Comment) | Organism |
---|---|
to crystalline state, chromatography and precipitation techniques | Rattus sp. |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Rattus sp. | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DL-2-hydroxybutyrate + O2 | - |
Rattus sp. | 2-oxobutyrate + H2O2 | - |
? | |
DL-2-hydroxycaproate + O2 | - |
Rattus sp. | 2-oxocaproate + H2O2 | - |
? | |
DL-2-hydroxyisocaproate + O2 | - |
Rattus sp. | 2-oxoisocaproate + H2O2 | - |
? | |
DL-2-hydroxyisovalerate + O2 | - |
Rattus sp. | 2-oxoisovalerate + H2O2 | - |
? | |
DL-2-hydroxyvalerate + O2 | - |
Rattus sp. | 2-oxovalerate + H2O2 | - |
? | |
DL-3-indolelactate + O2 | - |
Rattus sp. | 3-indolepyruvate + H2O2 | - |
? | |
DL-3-methoxy-4-hydroxymandelate + 2,6-dichlorophenolindophenol | - |
Rattus sp. | (3-methoxy-4-hydroxyphenyl)pyruvate + reduced 2,6-dichlorophenolindophenol | - |
? | |
DL-phenyllactate + O2 | - |
Rattus sp. | phenylpyruvate + H2O2 | - |
? | |
L-2-hydroxyisocaproate + O2 | - |
Rattus sp. | 2-oxoisocaproate + H2O2 | - |
? | |
L-2-hydroxyphenyllactate + O2 | - |
Rattus sp. | ? + H2O2 | - |
? | |
L-alanine + O2 | low activity | Rattus sp. | ? + H2O2 | - |
? | |
L-isoleucine + O2 | low activity | Rattus sp. | ? + H2O2 | - |
? | |
L-lactate + O2 | - |
Rattus sp. | pyruvate + H2O2 | - |
? | |
L-leucine + O2 | highest activity | Rattus sp. | ? + H2O2 | - |
? | |
L-mandelate + 2,6-dichlorophenolindophenol | - |
Rattus sp. | oxo(phenyl)acetic acid + reduced 2,6-dichlorophenolindophenol | - |
? | |
L-methionine + O2 | - |
Rattus sp. | ? + H2O2 | - |
? | |
L-phenylalanine + O2 | - |
Rattus sp. | ? + H2O2 | - |
? | |
L-tryptophan + O2 | - |
Rattus sp. | ? + H2O2 | - |
? | |
L-tyrosine + O2 | - |
Rattus sp. | ? + H2O2 | - |
? | |
L-valine + O2 | low activity | Rattus sp. | ? + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
L-amino acid oxidase | - |
Rattus sp. |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.433 | - |
L-lactate | - |
Rattus sp. |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
oxidation of L-lactate | Rattus sp. |
8.7 | - |
oxidation of L-leucine | Rattus sp. |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FMN | 2 mol FAD per mol enzyme | Rattus sp. |