BRENDA - Enzyme Database show
show all sequences of 1.1.1.B25

Enzymatic conversion of norsolorinic acid to averufin in aflatoxin biosynthesis

Yabe, K.; Nakamura, Y.; Nakajima, H.; Ando, Y.; Hamasaki, T.; Appl. Environ. Microbiol. 57, 1340-1345 (1991)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
norsolorinate + NADH + H+
Aspergillus parasiticus
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway
(1'S)-averantin + NAD+
-
-
?
norsolorinate + NADH + H+
Aspergillus parasiticus NIAH-26
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway
(1'S)-averantin + NAD+
-
-
?
norsolorinate + NADPH + H+
Aspergillus parasiticus
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway
(1'S)-averantin + NADP+
-
-
?
norsolorinate + NADPH + H+
Aspergillus parasiticus NIAH-26
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway
(1'S)-averantin + NADP+
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Aspergillus parasiticus
-
-
-
Aspergillus parasiticus NIAH-26
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
norsolorinate + NADH + H+
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway
721314
Aspergillus parasiticus
(1'S)-averantin + NAD+
-
-
-
?
norsolorinate + NADH + H+
assay with postmicrosome (cytosol) fraction. The reverse reaction is promoted by the addition of NAD+or NADP+
721314
Aspergillus parasiticus
(1'S)-averantin + NAD+
-
-
-
r
norsolorinate + NADH + H+
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway
721314
Aspergillus parasiticus NIAH-26
(1'S)-averantin + NAD+
-
-
-
?
norsolorinate + NADH + H+
assay with postmicrosome (cytosol) fraction. The reverse reaction is promoted by the addition of NAD+or NADP+
721314
Aspergillus parasiticus NIAH-26
(1'S)-averantin + NAD+
-
-
-
r
norsolorinate + NADPH + H+
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway
721314
Aspergillus parasiticus
(1'S)-averantin + NADP+
-
-
-
?
norsolorinate + NADPH + H+
assay with postmicrosome (cytosol) fraction. The reverse reaction is promoted by the addition of NAD+or NADP+
721314
Aspergillus parasiticus
(1'S)-averantin + NADP+
-
-
-
r
norsolorinate + NADPH + H+
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway
721314
Aspergillus parasiticus NIAH-26
(1'S)-averantin + NADP+
-
-
-
?
norsolorinate + NADPH + H+
assay with postmicrosome (cytosol) fraction. The reverse reaction is promoted by the addition of NAD+or NADP+
721314
Aspergillus parasiticus NIAH-26
(1'S)-averantin + NADP+
-
-
-
r
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
-
Aspergillus parasiticus
NADH
-
Aspergillus parasiticus
NADP+
-
Aspergillus parasiticus
NADPH
-
Aspergillus parasiticus
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
-
Aspergillus parasiticus
NADH
-
Aspergillus parasiticus
NADP+
-
Aspergillus parasiticus
NADPH
-
Aspergillus parasiticus
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
norsolorinate + NADH + H+
Aspergillus parasiticus
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway
(1'S)-averantin + NAD+
-
-
?
norsolorinate + NADH + H+
Aspergillus parasiticus NIAH-26
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway
(1'S)-averantin + NAD+
-
-
?
norsolorinate + NADPH + H+
Aspergillus parasiticus
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway
(1'S)-averantin + NADP+
-
-
?
norsolorinate + NADPH + H+
Aspergillus parasiticus NIAH-26
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway
(1'S)-averantin + NADP+
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
norsolorinate + NADH + H+
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway
721314
Aspergillus parasiticus
(1'S)-averantin + NAD+
-
-
-
?
norsolorinate + NADH + H+
assay with postmicrosome (cytosol) fraction. The reverse reaction is promoted by the addition of NAD+or NADP+
721314
Aspergillus parasiticus
(1'S)-averantin + NAD+
-
-
-
r
norsolorinate + NADH + H+
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway
721314
Aspergillus parasiticus NIAH-26
(1'S)-averantin + NAD+
-
-
-
?
norsolorinate + NADH + H+
assay with postmicrosome (cytosol) fraction. The reverse reaction is promoted by the addition of NAD+or NADP+
721314
Aspergillus parasiticus NIAH-26
(1'S)-averantin + NAD+
-
-
-
r
norsolorinate + NADPH + H+
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway
721314
Aspergillus parasiticus
(1'S)-averantin + NADP+
-
-
-
?
norsolorinate + NADPH + H+
assay with postmicrosome (cytosol) fraction. The reverse reaction is promoted by the addition of NAD+or NADP+
721314
Aspergillus parasiticus
(1'S)-averantin + NADP+
-
-
-
r
norsolorinate + NADPH + H+
the enzyme catalyzes a reaction in the aflatoxin biosynthesis pathway
721314
Aspergillus parasiticus NIAH-26
(1'S)-averantin + NADP+
-
-
-
?
norsolorinate + NADPH + H+
assay with postmicrosome (cytosol) fraction. The reverse reaction is promoted by the addition of NAD+or NADP+
721314
Aspergillus parasiticus NIAH-26
(1'S)-averantin + NADP+
-
-
-
r
Other publictions for EC 1.1.1.B25
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
721451
Lee
Subcellular localization of af ...
Aspergillus parasiticus, Aspergillus parasiticus SU-1
Arch. Microbiol.
181
204-214
2004
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4
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721326
Zhou
Enzymatic function of the nor- ...
Aspergillus parasiticus
Appl. Environ. Microbiol.
65
5639-5641
1999
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1
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1
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721320
Trail
Structural and functional anal ...
Aspergillus parasiticus, Aspergillus parasiticus SU-1
Appl. Environ. Microbiol.
60
4078-4085
1994
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1
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721316
Yabe
Stereochemistry during aflatox ...
Aspergillus parasiticus, Aspergillus parasiticus NIAH-26
Appl. Environ. Microbiol.
59
2486-2492
1993
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1
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1
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9
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2
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2
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721314
Yabe
Enzymatic conversion of norsol ...
Aspergillus parasiticus, Aspergillus parasiticus NIAH-26
Appl. Environ. Microbiol.
57
1340-1345
1991
-
-
-
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-
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-
4
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9
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8
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4
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4
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4
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8
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