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show all sequences of 1.1.1.B18

Genetic analysis around aminoalcohol dehydrogenase gene of Rhodococcus erythropolis MAK154: a putative GntR transcription factor in transcriptional regulation

Urano, N.; Kataoka, M.; Ishige, T.; Kita, S.; Sakamoto, K.; Shimizu, S.; Appl. Microbiol. Biotechnol. 89, 739-746 (2011)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
gene aadh, DNA and amino acid sequence determination and analysis, expression analysis
Rhodococcus erythropolis
Engineering
Amino acid exchange
Commentary
Organism
additional information
OrfE is a negative regulator that represses gene aadh expression in the absence of 1-amino-2-propanol. Construction of orfE disruption mutant and analysis of enzyme regulation in an OrfE-deficient mutant, overview
Rhodococcus erythropolis
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(2S)-2-(methylamino)-1-phenylpropan-1-one + NADPH + H+
Rhodococcus erythropolis
-
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol + NADP+
i.e. D-pseudoephedrine
-
-
(2S)-2-(methylamino)-1-phenylpropan-1-one + NADPH + H+
Rhodococcus erythropolis MAK154
-
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol + NADP+
i.e. D-pseudoephedrine
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Rhodococcus erythropolis
A1IG83
gene aadh
-
Rhodococcus erythropolis MAK154
A1IG83
gene aadh
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(2S)-2-(methylamino)-1-phenylpropan-1-one + NADPH + H+
-
724052
Rhodococcus erythropolis
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol + NADP+
i.e. D-pseudoephedrine
-
-
-
(2S)-2-(methylamino)-1-phenylpropan-1-one + NADPH + H+
-
724052
Rhodococcus erythropolis MAK154
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol + NADP+
i.e. D-pseudoephedrine
-
-
-
Cofactor
Cofactor
Commentary
Organism
Structure
NADP+
-
Rhodococcus erythropolis
NADPH
-
Rhodococcus erythropolis
Cloned(Commentary) (protein specific)
Commentary
Organism
gene aadh, DNA and amino acid sequence determination and analysis, expression analysis
Rhodococcus erythropolis
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADP+
-
Rhodococcus erythropolis
NADPH
-
Rhodococcus erythropolis
Engineering (protein specific)
Amino acid exchange
Commentary
Organism
additional information
OrfE is a negative regulator that represses gene aadh expression in the absence of 1-amino-2-propanol. Construction of orfE disruption mutant and analysis of enzyme regulation in an OrfE-deficient mutant, overview
Rhodococcus erythropolis
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(2S)-2-(methylamino)-1-phenylpropan-1-one + NADPH + H+
Rhodococcus erythropolis
-
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol + NADP+
i.e. D-pseudoephedrine
-
-
(2S)-2-(methylamino)-1-phenylpropan-1-one + NADPH + H+
Rhodococcus erythropolis MAK154
-
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol + NADP+
i.e. D-pseudoephedrine
-
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(2S)-2-(methylamino)-1-phenylpropan-1-one + NADPH + H+
-
724052
Rhodococcus erythropolis
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol + NADP+
i.e. D-pseudoephedrine
-
-
-
(2S)-2-(methylamino)-1-phenylpropan-1-one + NADPH + H+
-
724052
Rhodococcus erythropolis MAK154
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol + NADP+
i.e. D-pseudoephedrine
-
-
-
Expression
Organism
Commentary
Expression
Rhodococcus erythropolis
OrfE is a negative regulator that represses gene aadh expression in the absence of 1-amino-2-propanol
down
Rhodococcus erythropolis
the enzyme is induced by the addition of several aminoalcohols, such as 1-amino-2-propanol
up
General Information
General Information
Commentary
Organism
metabolism
the enzyme participates in aminoalcohol or aminoketone metabolism in the organism
Rhodococcus erythropolis
additional information
OrfE is a negative regulator that represses gene aadh expression in the absence of 1-amino-2-propanol, analysis of enzyme regulation in tan OrfE-deficient mutant, overview
Rhodococcus erythropolis
General Information (protein specific)
General Information
Commentary
Organism
metabolism
the enzyme participates in aminoalcohol or aminoketone metabolism in the organism
Rhodococcus erythropolis
additional information
OrfE is a negative regulator that represses gene aadh expression in the absence of 1-amino-2-propanol, analysis of enzyme regulation in tan OrfE-deficient mutant, overview
Rhodococcus erythropolis
Expression (protein specific)
Organism
Commentary
Expression
Rhodococcus erythropolis
OrfE is a negative regulator that represses gene aadh expression in the absence of 1-amino-2-propanol
down
Rhodococcus erythropolis
the enzyme is induced by the addition of several aminoalcohols, such as 1-amino-2-propanol
up
Other publictions for EC 1.1.1.B18
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
724052
Urano
Genetic analysis around aminoa ...
Rhodococcus erythropolis, Rhodococcus erythropolis MAK154
Appl. Microbiol. Biotechnol.
89
739-746
2011
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1
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1
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4
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2
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2
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1
2
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1
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2
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2
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-
-
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2
2
2
2
-
-
713441
Lin
-
Enantioselective synthesis of ...
Rhodococcus erythropolis, Rhodococcus erythropolis BCRC 10909
Process Biochem.
45
1529-1536
2010
-
1
-
-
-
-
-
-
-
-
2
-
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2
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-
-
-
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2
1
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-
-
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1
-
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1
-
1
-
-
-
-
-
-
-
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2
-
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2
1
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695805
Kataoka
Cloning and expression of the ...
Rhodococcus erythropolis
Appl. Microbiol. Biotechnol.
80
597-604
2008
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-
1
-
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1
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1
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1
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1
1
1
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1
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1
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1
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1
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1
1
1
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1
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712916
Kataoka
A novel NADP+-dependent L-1-am ...
Rhodococcus erythropolis, Rhodococcus erythropolis MAK154
Lett. Appl. Microbiol.
43
430-455
2006
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-
-
-
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2
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6
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1
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1
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10
1
2
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1
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2
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1
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1
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10
1
2
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1
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1
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1
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