BRENDA - Reference to 1.1.1.88; Id = 287504

3 A resolution, 3 dimers packed along three-fold crystallographic axis, hexamer

Pseudomonas mevalonii

-

(R)-mevalonate + CoA + 2 NAD+

with mevalonate as sole source of carbon enzyme acts as a biodegradative enzyme

287504

Pseudomonas mevalonii

(S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+

-

hexamer

3alpha2, XSA

Pseudomonas mevalonii

6

-

oxidative acylation of mevalonate with NADP+ as cofactor

Pseudomonas mevalonii

9

-

oxidative acylation of mevalonate

Pseudomonas mevalonii

NAD+

-

Pseudomonas mevalonii

NADH

reverse reaction

Pseudomonas mevalonii

NAD+

-

Pseudomonas mevalonii

NADH

reverse reaction

Pseudomonas mevalonii

3 A resolution, 3 dimers packed along three-fold crystallographic axis, hexamer

Pseudomonas mevalonii

(R)-mevalonate + CoA + 2 NAD+

with mevalonate as sole source of carbon enzyme acts as a biodegradative enzyme

287504

Pseudomonas mevalonii

(S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+

-

hexamer

3alpha2, XSA

Pseudomonas mevalonii

6

-

oxidative acylation of mevalonate with NADP+ as cofactor

Pseudomonas mevalonii

9

-

oxidative acylation of mevalonate

Pseudomonas mevalonii

723092

Ma

Optimization of a heterologous ...

Bordetella petrii, Delftia acidovorans, Pseudomonas mevalonii

Metab. Eng.

13

588-597

2011

-

3

-

7

-

4

-

3

-

3

-

3

-

9

-

9

-

3

-

4

-

3

-

3

-

3

-

3

-

712189

Perchellet

Novel synthetic inhibitors of ...

Homo sapiens, Mus musculus

Int. J. Mol. Med.

24

633-643

2009

-

8

-

2

-

1

-

1

-

8

-

1

-

1

-

712196

Yu

-

Expression of low-density lipo ...

Homo sapiens

Int. J. Ophthal.

9

284-285

2009

-

1

-

1

-

2

-

1

-

2

-

1

-

1

-

712560

Martini

3-Hydroxy 3-methylglutaryl coe ...

Rattus norvegicus

J. Cell. Physiol.

220

524-530

2009

-

1

-

2

-

2

-

1

-

712670

Slotta

Inhibition of 3-hydroxy-3-meth ...

Mus musculus

J. Investig. Med.

57

645-649

2009

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

687173

Azenabor

Chlamydia trachomatis Infectio ...

Homo sapiens

Int. J. Med. Sci.

4

223-231

2007

-

1

-

1

-

1

-

688564

Shirai

Effect of docosahexaenoic acid ...

Mus musculus

J. Nutr. Biochem.

18

488-494

2007

1

-

1

-

2

1

-

1

-

1

-

1

-

2

1

-

1

-

1

-

689467

Kevei

3-hydroxy-3-methylglutaryl coe ...

Medicago truncatula

Plant Cell

19

3974-3989

2007

-

1

-

1

-

1

-

5

-

2

-

1

-

1

-

1

-

2

-

657303

Hedl

Inhibition of the Class II HMG ...

Pseudomonas mevalonii

Protein Sci.

13

1693-1697

2004

-

6

-

1

-

1

-

1

-

2

9

-

2

-

6

9

-

1

-

654225

Ayora-Talavera

Overexpression in Catharanthus ...

Mesocricetus auratus

Appl. Biochem. Biotechnol.

97

135-145

2002

-

1

-

2

-

2

-

3

-

2

-

1

2

-

2

-

3

-

656615

Crane

-

Regulated accumulation of 3-hy ...

Solanum tuberosum

J. Plant Physiol.

159

1301-1307

2002

2

-

2

-

1

-

1

-

2

-

1

-

2

-

1

-

2

-

1

-

2

-

287507

Tabernero

Substrate-induced closure of t ...

Pseudomonas mevalonii

Proc. Natl. Acad. Sci. USA

96

7167-7177

1999

-

1

-

2

-

2

-

287508

Bochar

Aminoethylcysteine can replace ...

Pseudomonas mevalonii

Biochemistry

38

8879-8883

1999

-

1

-

2

-

2

-

287506

Rogers

Active form of Pseudomonas mev ...

Pseudomonas mevalonii

Biochem. Mol. Med.

61

114-120

1997

-

1

-

1

3

-

2

1

-

2

-

1

-

1

2

1

-

2

-

1

-

2

1

3

-

2

1

-

1

2

1

-

287505

Friesen

Structural determinants of nuc ...

Pseudomonas mevalonii

Biochemistry

35

11945-11950

1996

-

1

-

13

-

2

-

2

-

4

-

1

4

-

13

-

2

-

287504

Lawrence

Crystal structure of Pseudomon ...

Pseudomonas mevalonii

Science

268

1758-1762

1995

-

1

-

1

-

1

-

2

-

2

-

2

1

-

1

-

2

-

287503

Sato

Replacement of serine-871 of h ...

Mesocricetus auratus

Proc. Natl. Acad. Sci. USA

90

9261-9265

1993

-

1

-

1

-

1

-

1

-

2

-

1

-

2

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

2

-

2

-

287502

Darnay

Identification of the catalyti ...

Pseudomonas mevalonii

J. Biol. Chem.

267

15064-15070

1992

-

1

4

1

-

15

-

1

-

1

-

1

-

6

-

2

-

5

-

2

-

1

2

1

4

1

-

15

-

1

-

6

-

2

-

5

-

287499

Jordan-Starck

Pseudomonas mevalonii 3-hydrox ...

Pseudomonas mevalonii

J. Biol. Chem.

264

17913-17918

1989

2

-

1

-

1

-

8

1

-

4

-

1

-

1

2

-

2

-

2

-

1

2

-

1

-

8

1

-

1

-

1

2

-

287500

Jordan-Starck

Role of cysteine residues in P ...

Pseudomonas mevalonii

J. Biol. Chem.

264

17919-17923

1989

-

1

-

3

-

1

-

4

-

1

-

2

-

1

2

-

3

-

4

-

1

-

287501

Beach

Cloning, sequencing, and overe ...

Pseudomonas mevalonii

J. Bacteriol.

171

2994 - 3001

1989

-

1

-

1

-

3

-

2

-

1

2

-

1

-

287498

Gill

Mevalonate utilization in Pseu ...

Pseudomonas mevalonii

J. Biol. Chem.

260

9393-9398

1985

-

4

1

-

2

1

-

1

-

1

2

1

-

1

-

2

-

2

-

4

-

1

-

1

-

2

1

-

1

2

1

-

1

-

287497

Rodwell

S-3-Hydroxy-3-methylglutaryl-C ...

Pseudomonas mevalonii

Methods Enzymol.

71

480-486

1981

-

1

10

-

1

-

1

-

1

-

3

-

1

-

2

-

2

-

2

-

1

-

10

-

1

-

1

-

3

-

1

-

2

-

287496

Bensch

Purification and properties of ...

Pseudomonas mevalonii

J. Biol. Chem.

245

3755-3762

1970

-

2

1

10

1

-

1

-

2

-

1

-

2

-

2

-

2

-

1

-

10

1

-

2

-

1

-

287495

Fimognari

-

Substrate-competitive inhibiti ...

Mycobacterium sp., Mycobacterium sp. s4, Pseudomonas mevalonii

Biochemistry

4

2086-2090

1965

-

12

6

2

1

-

3

-

2

7

-

2

-

3

-

3

-

12

-

6

2

1

-

2

7

-

2

-

Crystal structure of Pseudomonas mevalonii HMG-CoA reductase at 3.0 Angstrom resolution

Data extracted from this reference: