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Literature summary for 1.1.1.87 extracted from

  • Sandell, L.L.; Sanderson, B.W.; Moiseyev, G.; Johnson, T.; Mushegian, A.; Young, K.; Rey, J.P.; Ma, J.X.; Staehling-Hampton, K.; Trainor, P.A.
    RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development (2007), Genes Dev., 21, 1113-1124.
    View publication on PubMedView publication on EuropePMC
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Protein Variants

Protein Variants Comment Organism
additional information trex mutant allele, T to C exchange at nucleotide 251. Midgestation lethal mutant which displays craniofacial, limb, and organ abnormalities due to insufficient retinoic acid signaling Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus retinol dehydrogenase 10 activity is critical for spatiotemporal synthesis of retinoic acid during embrogenesis ?
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Organism

Organism UniProt Comment Textmining
Mus musculus
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 isoform Rdh10
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information retinol dehydrogenase 10 activity is critical for spatiotemporal synthesis of retinoic acid during embrogenesis Mus musculus ?
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 ?